In a large bowl, combine the drained and flaked salmon, panko breadcrumbs, red onion, dill, mayonnaise, dijon mustard, egg, lemon juice, garlic powder, salt, and black pepper. Mix gently with a fork until everything is well combined. Be careful not to overmix or the patties will become dense.
Form the mixture into 8 evenly sized patties, about 3 inches wide and 3/4-inch thick. Press them firmly so they hold together. Place them on a plate and refrigerate for 15 minutes to help them set.
Preheat the air fryer to 375°F for 2 minutes.
Spray the air fryer basket with cooking spray. Place the salmon patties in a single layer with space between each one. Spray the tops of the patties lightly with cooking spray.
Air fry for 8 minutes, then gently flip each patty and cook for 4 to 5 minutes more until both sides are golden brown and crispy.
Serve the salmon patties warm with lemon wedges and a side of tartar sauce or creamy dill yogurt sauce.