Slice the chicken breasts into bite-sized pieces and place them in a bowl with the buttermilk to soak for 10 minutes.
In a separate bowl, whisk together the cornstarch, smoked paprika, garlic powder, and salt.
Remove the chicken pieces from the buttermilk, letting excess drip off, and toss them in the cornstarch mixture until fully coated.
Spray the air fryer basket with cooking spray, arrange the chicken in a single layer, and spray the tops of the chicken.
Air fry at 380F for 12 minutes, shaking the basket halfway through, until crispy and cooked through.
Whisk the honey, hot sauce, and red pepper flakes in a large bowl, then toss the warm crispy chicken in the sauce before serving.