Soak chicken tenders in buttermilk for at least 30 minutes in the refrigerator.
Set up three bowls: flour in first, remaining buttermilk with soaked chicken in second (reserve some), and panko breadcrumbs mixed with parmesan, paprika, garlic powder, and salt in third.
Remove each tender from buttermilk, dredge in flour, dip back in buttermilk, then press firmly into breadcrumb mixture coating all sides.
Spray air fryer basket with cooking spray. Arrange tenders in a single layer without overlapping and spray tops generously with cooking spray.
Air fry at 400°F for 10-12 minutes, flipping halfway through, until golden brown and internal temperature reaches 165°F. Serve with your favorite dipping sauce.