Mix the flour, garlic powder, black pepper, and smoked paprika in a bowl.
Cover the shrimp with the mixture.
Place the shrimp in the fridge for 20 minutes so the coating sticks well.
To make the sauce, place the buffalo sauce and butter in a microwave-safe bowl. Microwave in 20-second intervals until the butter melts.
Spray the air fryer basket with cooking oil. Place the shrimp inside (in a single layer to make sure they cook evenly). Air fry at 400F for 2-3 minutes. Then, flip them and cook for 2-3 more minutes.
Remove the shrimp from the air fryer and cover them with the sauce. Serve hot, and enjoy!